Our research program spans several areas of organic chemistry, including photochemistry and photocatalysis, asymmetric catalysis, organosulfur and organoboron chemistry, natural product synthesis and medicinal chemistry, as well as the chemistry of nitroxy compounds and nitrogen heterocycles. The unifying theme of our research is the development of simple and efficient synthetic methods that streamline access to complex organic molecules. We use a range of experimental and computational methods to gain mechanistic understanding and catalyze the discovery of new chemical reactivity.
Nand, S.; Dhakal, S. K.; Trevino, R.; Dhungana, B. R.; Thompson, W. T.; Giri, C. K.; Nguyen, V. T. B.; Sanchez, J. A.; Elerian, R.; Moran, D. P.; Skaria, T. T.; Arman, H. D.; Larionov, O. V. Asymmetric Radical Sulfinylation via Stereoablative Sulfinyl Radical Generation. ChemRxiv 2026, DOI: 10.26434/chemrxiv.15003968/v1.
Nguyen, V. D.; Nand, S.; Trevino, R.; Porey, A.; Thompson, W. T.; Haug, G. C.; Fremin, S. O.; Dhakal, S. K.; Hughes, W. B.; Moran, D. P.; Lakey-Beitia, J.; Giri, C. K.; Manning-Lorino, P.; Greco, S. G.; Arman, H. D.; Larionov, O. V. Cyclic Sulfone Ring Remodeling Enables Molecular Shape Diversity-Oriented Synthesis of Privileged Biaryl and Oligoaryl Motifs. ChemRxiv 2026, DOI: 10.26434/chemrxiv.15000097/v1. (Accepted in Nat. Commun.)
Wang, Y.; Dhungana, B. R.; Trevino, R.; Sun, Y.; Yang, W.; Zhai, H.; Nand, S.; Nguyen, V. T. B.; Geng, H.; Sanchez, J. A.; Huang, C.; Elerian, R.; He, M.; Cheng, M.; Larionov, O. V.; Jin, S. Tricomponent α-Carbonyl Alkylation by a Cobalt-Catalyzed Polar–Radical and Radical–Polar Crossover Cascade. J. Am. Chem. Soc. 2026, DOI: 10.1021/jacs.6c06698.
Robert A. Welch Distinguished University Chair in Chemistry
Department of Chemistry
The University of Texas at San Antonio
One UTSA Circle, San Antonio, TX 78249