Synthetic Methodology and Catalysis

Research

Our research program spans several areas of organic chemistry, including photochemistry and photocatalysis, asymmetric catalysis, organosulfur and organoboron chemistry, natural product synthesis and medicinal chemistry, as well as the chemistry of nitroxy compounds and nitrogen heterocycles. The unifying theme of our research is the development of simple and efficient synthetic methods that streamline access to complex organic molecules. We use a range of experimental and computational methods to gain mechanistic understanding and catalyze the discovery of new chemical reactivity.

Our Team

Oleg Larionov

Professor and Robert A. Welch Distinguished University Chair in Chemistry

Arka Porey

Postdoctoral Researcher

Sachchida Nand

Postdoctoral researcher

Recent Publications

Azaanthraquinones redefine the scope of photocatalytic PCET for direct decarboxylative functionalization

Azaanthraquinones redefine the scope of photocatalytic PCET for direct decarboxylative functionalization

Nand, S.; Larionov, O. V.; Azaanthraquinones redefine the scope of photocatalytic PCET for direct decarboxylative functionalization. Chem 2025, 11, 102871.

Dispersion-Enhanced Nitrogen-Centered Photocatalysis of the Direct Hydrogen Atom Transfer

Dispersion-Enhanced Nitrogen-Centered Photocatalysis of the Direct Hydrogen Atom Transfer

Zhang, J.; Zhuang, K.; Trevino, R.; Dhungana, B. R.; Sun, H.; Yin, S.; Li, Y.; Sanchez, J. A.; Xia, X.; Elerian, R.; Sun, Y.; Fremin, S. O.; Huang, C.; He, M.; Cheng, M.; Larionov, O. V.; Jin, S. Dispersion-Enhanced Nitrogen-Centered Photocatalysis of the Direct Hydrogen Atom Transfer. ChemRxiv. 2025,
DOI: 10.26434/chemrxiv-2025-tf0gq.

Visible Light-Induced Cytotoxicity of a Thiophene–Benzothiadiazole-Based Conjugated Oligoelectrolyte in Cancer Cells

Visible Light-Induced Cytotoxicity of a Thiophene–Benzothiadiazole-Based Conjugated Oligoelectrolyte in Cancer Cells

Jana, K.; Barboza-Ramos, I.; Bush, J. E. M.; Wilkinson, N. J.; Porey, A.; Wherritt, D. J.; Larionov, O. V.; Risinger, A. L.; Schanze, K. S. Visible Light-Induced Cytotoxicity of a Thiophene–Benzothiadiazole-Based Conjugated Oligoelectrolyte in Cancer Cells. ACS Appl. Bio Mater. 2025, DOI: 10.1021/acsabm.5c01363.

Contact

Dr. Oleg Larionov

Robert A. Welch Distinguished University Chair in Chemistry
Department of Chemistry
The University of Texas at San Antonio
One UTSA Circle, San Antonio, TX 78249